Evidence map›Paper›PMID 42495692›Full record

ArticlePNAS nexus2026

Functional role of a structural water in the elevator domain of dicarboxylate transporter VcINDY.

Andrew Daab, Yan Li, Jennifer J Marden, Jinmei Song, David B Sauer, Da-Neng Wang, Christopher Mulligan

Abstract read
In one paragraph

Article in PNAS nexus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew DaabSchool of Natural Sciences, University of Kent, Canterbury, Kent CT2 7NH, United Kingdom.ORCID https://orcid.org/0009-0006-9320-7378
Yan LiDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID https://orcid.org/0000-0001-9209-2288
Jennifer J MardenDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID https://orcid.org/0000-0002-7221-2454
Jinmei SongDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID https://orcid.org/0000-0001-8658-3590
David B SauerCentre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX1 3QU, United Kingdom.ORCID https://orcid.org/0000-0001-9291-4640
Da-Neng WangDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID https://orcid.org/0000-0002-6496-4699
Christopher MulliganSchool of Natural Sciences, University of Kent, Canterbury, Kent CT2 7NH, United Kingdom.ORCID https://orcid.org/0000-0001-5157-4651

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Cheongeun Oh · 1985 to 2026
$83.1M
Transport Cycle and Inhibition of Human Na+-dicarboxylate Cotransporter NaDC3R01NS108151 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DANENG WANG · 2018 to 2026
$4.1M
Transport Mechanisms and Inhibition of Efflux Pumps in Pathogenic OrganismsR01AI165782 · NIAID · NEW YORK UNIVERSITY · PI SHOHEI KOIDE, Nathaniel J. Traaseth · 2022 to 2026
$4.0M
Dynamics and mechanism of sodium-dependent carboxylate transportersR01DK135088 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Ruben L Gonzalez, Emad Tajkhorshid · 2023 to 2026
$2.6M
Structural basis of the Ragulator-Rag GTPase complex as a platform for mTOR activation on the lysosomal surfaceR01GM121994 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WANG, DANENG · 2017 to 2020
$1.5M
NCI NIH HHS P30 CA016087NIAID NIH HHS R01 AI165782NIDDK NIH HHS R01 DK135088NIGMS NIH HHS R01 GM121994NINDS NIH HHS R01 NS108151
6 · The paper itself

Abstract

The divalent anion sodium symporter (DASS) family mediates the uptake of Krebs cycle intermediates and sulfate and influences adiposity, insulin resistance, and metabolism in mammals. While Na

Identifiers

PMID42495692
PMCPMC13394699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.