Evidence map›Paper›PMID 42495527›Full record

ArticleiScience2026

Rheumatoid arthritis burden in 129 low- and middle-income countries from 1990 to 2023.

Hongnian Wang, Mingyang Zhang, Xiong Ke, Zichao Wang, Lijuan Wu

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hongnian WangKey Laboratory of Digital-Intelligent Disease Surveillance and Health Governance, North Sichuan Medical College, Nanchong, China.
Mingyang ZhangSchool of Social Sciences, Henan Normal University, Xinxiang, China.
Xiong KeKey Laboratory of Digital-Intelligent Disease Surveillance and Health Governance, North Sichuan Medical College, Nanchong, China.
Zichao WangDepartment of Epidemiology and Statistics, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Lijuan WuInstitute of Sciences in Emergency Medicine, Department of Emergency Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) causes substantial disability in low- and middle-income countries (LMICs), which account for most of the global population. Using Global Burden of Disease (GBD) 2023 data, we assessed RA prevalence, incidence, mortality, and disability-adjusted life-year (DALY) rates across 129 LMICs from 1990 to 2023 and projected trends to 2050. Countries were stratified by gross national income (GNI) into low-income, lower-middle-income, and upper-middle-income groups. In 2023, RA affected 12.6 million individuals, with prevalence in upper-middle-income countries being 4.1-fold higher than in low-income countries. Death rates converged across income groups, while absolute inequality in prevalence widened and inequality in mortality narrowed. Projections to 2050 indicated declining mortality in low-income settings but increasing in middle-income countries. Therefore, it is necessary to improve diagnostic capacity in low-income settings and medication affordability in middle-income countries.

Indexed as

arthritisdeveloping countriesglobal burden of diseasehealth equityhealth services accessibilitymortalityrheumatoid

Identifiers

PMID42495527
PMCPMC13392949

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.