Evidence map›Paper›PMID 42495487›Full record

ArticleCureus2026

The Use of an Omental Flap in the Management of Complex Thoracic Aortic Infections.

Zachary Brennan, Tyler J Wallen, Thomas M Beaver, Eric I Jeng, Tomas D Martin, George J Arnaoutakis

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zachary BrennanDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, USA.
Tyler J WallenDepartment of Surgery, Division of Cardiovascular Surgery, Penn Medicine, Philadelphia, USA.
Thomas M BeaverDepartment of Surgery, Division of Cardiovascular Surgery, University of Florida College of Medicine, Gainesville, USA.
Eric I JengDepartment of Surgery, Division of Cardiovascular Surgery, University of Florida College of Medicine, Gainesville, USA.
Tomas D MartinDepartment of Surgery, Division of Cardiovascular Surgery, University of Florida College of Medicine, Gainesville, USA.
George J ArnaoutakisDepartment of Surgery and Perioperative Care, Division of Cardiovascular and Thoracic Surgery, Dell Medical School, The University of Texas at Austin, Austin, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose Recurrent valvular endocarditis and thoracic aortic graft infection (TAGI) present complex clinical problems with difficult management options and poor reported outcomes. Omental flap coverage has been described for these infections, but published experience remains limited. The purpose of this study was to describe our institutional experience with staged mediastinal antibiotic irrigation followed by delayed mediastinal omental flap coverage. Methods We performed a retrospective review of a prospectively maintained institutional database. Adult patients treated at a single institution from January 1, 2017, through December 31, 2019, were included if they underwent operative management for recurrent valvular endocarditis and/or TAGI with mediastinal antibiotic irrigation followed by planned, delayed mediastinal omental flap coverage. Patients were excluded if they were managed nonoperatively, underwent surgery without this staged strategy, had isolated superficial sternal wound infection without graft or valvular involvement, or had insufficient documentation to determine 30-day outcomes. Results Seventeen patients were treated with mediastinal antibiotic irrigation followed by delayed omental flap coverage. Thirty-day mortality was 1/17 (5.9%). Major complications within 30 days occurred in 4/17 (23.5%), including renal failure requiring hemodialysis in 2/17 (11.8%), stroke in 1/17 (5.9%), and reoperation for recurrent infection in 1/17 (5.9%). The composite 30-day major adverse event rate, defined as death, stroke, renal failure requiring hemodialysis, or reoperation for recurrent infection, was 5/17 (29.4%). Conclusions In this single-center series, staged mediastinal antibiotic irrigation followed by delayed omental flap coverage was feasible and was associated with acceptable short-term mortality and complication rates. Further study is needed to determine the optimal timing and patient selection criteria for omental flap coverage in this setting.

Indexed as

aortic surgeryomental flapprosthetic infectionrecurrent endocarditisthoracic aortic graft infection

Identifiers

PMID42495487
PMCPMC13394616

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.