Evidence map›Paper›PMID 42495379›Full record

ArticleACS omega2026

Contrasting Biofilm-Modulating Effects of Polymeric Quaternary Ammonium Compounds on the Pathogenic Yeasts

Andreas Schelhorn, Josef Achhammer, Denis Hirsch, Jan-Christoph Walter, Daniel Gruber, Ann-Kathrin Kissmann, Frank Rosenau, Ulrich Ziener

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andreas SchelhornInstitute of Organic Chemistry III-Macromolecular Chemistry and Organic Materials, University of Ulm, Albert-Einstein-Allee 11, D-89081 Ulm, Germany.
Josef AchhammerInstitute of Organic Chemistry III-Macromolecular Chemistry and Organic Materials, University of Ulm, Albert-Einstein-Allee 11, D-89081 Ulm, Germany.
Denis HirschInstitute of Organic Chemistry III-Macromolecular Chemistry and Organic Materials, University of Ulm, Albert-Einstein-Allee 11, D-89081 Ulm, Germany.
Jan-Christoph WalterInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Daniel GruberInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Ann-Kathrin KissmannInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Frank RosenauInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID https://orcid.org/0000-0002-9297-6419
Ulrich ZienerInstitute of Organic Chemistry III-Macromolecular Chemistry and Organic Materials, University of Ulm, Albert-Einstein-Allee 11, D-89081 Ulm, Germany.ORCID https://orcid.org/0000-0001-7582-1143

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quaternary ammonium compounds (QACs), particularly in polymeric form (polyQACs), offer a broad spectrum of antimicrobial activity, e.g., via electrostatic membrane interaction. On the other hand, adamantane derivatives are notable for their rigid, lipophilic structure and exhibit a broad spectrum of biological activities. In this multidisciplinary study, we report the synthesis of three structurally defined and related polyQACs with and without azaadamantane units differing primarily in hydrophilicity and flexibility. We demonstrate that one of these compounds, poly-(vinylbenzyltrimethylammonium chloride)

Identifiers

PMID42495379
PMCPMC13393035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.