Evidence map›Paper›PMID 42495295›Full record

ArticleACS omega2026

Repurposing 6‑Anilinopurine Derivatives That Exhibit PfHDAC1 Inhibition and Antimalarial Activity against Asexual and Sexual Stages of

Bárbara K M Dias, Pedro N Maiolini, Natacha Diesca Santos, Karoline B Waitman, Maurício T Tavares, João P F Verotti, Mônica F Z J Toledo, Thales Kronenberger, Roberto Parise-Filho, Célia R S Garcia

Abstract read
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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bárbara K M DiasDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Pedro N MaioliniDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Natacha Diesca SantosDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Karoline B WaitmanDepartment of Pharmacy, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Maurício T TavaresDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston 02215, United States.ORCID https://orcid.org/0000-0002-4400-7787
João P F VerottiDepartment of Pharmacy, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Mônica F Z J ToledoDepartment of Pharmacy, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.ORCID https://orcid.org/0000-0001-7974-4480
Thales KronenbergerInterfaculty Institute of Microbiology and Infection Medicine (IMIT), University of Tübingen, Tübingen 72076, Germany.ORCID https://orcid.org/0000-0001-6933-7590
Roberto Parise-FilhoDepartment of Pharmacy, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.ORCID https://orcid.org/0000-0002-9311-7245
Célia R S GarciaDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.ORCID https://orcid.org/0000-0003-2825-1701

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is a disease caused by protozoans of the genus

Identifiers

PMID42495295
PMCPMC13393398

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.