ArticleACS omega2026
Sodium Alginate Nanogels Encapsulating Cholecalciferol (Vitamin D3): A Topical Therapeutic Approach Targeting LOX IMVI and A431 Skin Cancer Cells.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study explores sodium alginate nanogels encapsulating cholecalciferol (vitamin D3) as a novel topical therapeutic for skin cancer, targeting LOX IMVI (melanoma) and A431 (epidermoid carcinoma) cell lines. Nanogels were prepared using magnetic stirring and sonication, resulting in a uniform dispersion and enhanced stability. Physicochemical characterization revealed a particle size of 67.6 ± 13.43 nm, a polydispersity index (PDI) of 0.30 ± 0.02, and a ζ-potential of -25.00 ± 2.00 mV, confirming good colloidal stability and suitability for topical application. In vitro drug release studies demonstrated a sustained-release profile, with 89.73 ± 2.1% cholecalciferol released over 34 h, as predicted by a first-order kinetic model (
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Registered trials
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