Evidence map›Paper›PMID 42495099›Full record

ArticleThe Pan African medical journal2026

Actinomycetoma of the wrist: diagnostic insights from a pathology perspective (case report).

Aaliya Sheikh, Keshao Hiwale, Shailly Tiwari

Abstract readCase Reports
In one paragraph

Article in The Pan African medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aaliya SheikhDepartment of Pathology, Datta Meghe Institute of Medical Science and Research, Sawangi Meghe, Wardha, Maharashtra, India.
Keshao HiwaleDepartment of Pathology, Datta Meghe Institute of Medical Science and Research, Sawangi Meghe, Wardha, Maharashtra, India.
Shailly TiwariDepartment of Pathology, Datta Meghe Institute of Medical Science and Research, Sawangi Meghe, Wardha, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Actinomycetoma is a chronic, progressive subcutaneous infection caused by filamentous bacteria of the Actinomycetales order, characterized by tumefaction, sinuses, and grains. We report a rare case of actinomycetoma affecting the wrist of a 45-year-old male, which presented as a chronic, slowly enlarging swelling with multiple discharging sinuses. Initial clinical suspicion was broad, encompassing various chronic infections or soft tissue tumors. However, definitive diagnosis was established through meticulous histopathological examination of a biopsy specimen, revealing characteristic "sulphur grains" composed of a basophilic bacterial colony surrounded by Splendore-Hoeppli phenomenon, alongside a mixed inflammatory infiltrate. Culture subsequently confirmed Nocardia brasiliensis. This case underscores the crucial role of integrated histopathology and microbiology in distinguishing actinomycetoma from other chronic granulomatous conditions, particularly in atypical anatomical locations, ensuring timely and appropriate therapeutic intervention.

Indexed as

MycetomaNocardiaNocardia InfectionsWristBiopsyHumansMaleMiddle AgedActinomycetomacase reportNocardia brasiliensissulphur grainswrist

Identifiers

PMID42495099
PMCPMC13391426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.