Perioperative dynamic EEG patterns correlated with changes in cognitive subdomains.

Duygu Aydin, Mariana Thedim, Chiewlin Liew, Gerhard Schneider, Susana Vacas, Matthias Kreuzer

Abstract read

In one paragraph

Article in Clinical neurophysiology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

The Monitoring Paradox: Frontal Electroencephalography Reveals Profound Cortical Depression Despite Cardiovascular Stability in Dogs Undergoing Tibial Plateau Leveling Osteotomy with Isoflurane Anesthesia and Multimodal Analgesic Protocols.Veterinary sciences · 2026
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Duygu AydinDepartment of Anesthesiology and Intensive Care, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich 81675, Germany.

Mariana ThedimDepartment of Anesthesiology, Mass General Brigham, Harvard Medical School, 55 Fruit Street 444GRB, Boston, MA 02114, USA.

Chiewlin LiewDepartment of Anesthesiology and Perioperative Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Gerhard SchneiderDepartment of Anesthesiology and Intensive Care, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich 81675, Germany.

Susana VacasDepartment of Anesthesiology, Mass General Brigham, Harvard Medical School, 55 Fruit Street 444GRB, Boston, MA 02114, USA.

Matthias KreuzerDepartment of Anesthesiology and Intensive Care, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich 81675, Germany.

Funding

Mechanisms Mediating Postoperative Neurocognitive DisordersK23GM132795 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VACAS, SUSANA · 2019 to 2023

$1.0M

NIGMS NIH HHS K23 GM132795

6 · The paper itself

Abstract

Objective: Surgery and anesthesia can be associated with postoperative neurological injury, especially in individuals with diminished cognitive reserve. Timely identification of at-risk patients enables deployment of preventive strategies. Despite consistent recommendations, perioperative cognitive risk assessment remains largely overlooked. We explored which dynamic electroencephalogram (EEG) patterns are correlated with cognitive subdomains significantly affected by surgery and anesthesia. Methods: This was a secondary analysis of two prospective observational studies that included patients undergoing elective laparoscopic abdominal or pelvic surgery under general anesthesia. Cognition was assessed using the Mini-Mental State Exam, 2nd edition (MMSE-2) and the Montreal Cognitive Assessment (MoCA) within one week before and up to 48 h after surgery. Frontal EEG was recorded pre-induction to extubation. Cognitive subdomains and EEG changes were explored using linear regression and accuracy analyses. Results: Data were obtained from 23 surgical patients (median [IQR] age, 63 [16] years; 52% female). Auditory-verbal delayed recall (MMSE-2, Conclusion: Dynamic EEG patterns were correlated with processing speed changes. Integrating EEG into perioperative risk assessment may contribute to early identification of vulnerability. Significance: This study demonstrates the correlation between changes in perioperative EEG and cognitive subdomains.

Indexed as

ElectroencephalographyMini-mental state examMontreal cognitive assessmentPerioperative risk assessment

Identifiers

PMID42494977

DOI10.1016/j.cnp.2026.07.009

PMCPMC13393008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.