A Case Report of an Asymptomatic Cecum Ulceration Colonoscopically and Radiologically Mimicking Inflammatory Bowel Disease Caused by Amebic Colitis.

Introduction: Amebiasis is a disease caused by the protozoan parasite Case Presentation: We report a case of amebic colitis in a 62-year-old male who underwent routine colonoscopy, which revealed an ulceration in the cecum region. He was asymptomatic at presentation and had normal laboratory findings. The case was provisionally diagnosed as inflammatory bowel disease and received oral metronidazole and probiotics. At follow-up endoscopy, the ulceration had worsened. Biopsy from the margin of the ileocecal ulcer confirmed abundant amebic trophozoites. The patient was treated with metronidazole for 14 days. A follow-up colonoscopy after treatment showed that the lesions were completely healed. Conclusion: This case highlights the challenges of diagnosing amebic colitis. Amoebic colitis shows significant variation in presenting symptoms, and current diagnostic methods have limited sensitivity. The absence of obvious symptoms in this patient further increased the diagnostic difficulty. We recommend that clinicians consider invasive amebiasis in their list of differential diagnosis even in asymptomatic patients presenting with colonic ulceration.