Evidence map›Paper›PMID 42494752›Full record

ArticleBioactive materials2026

NIR-II-activated supramolecular LDH nanoarchitecture integrated with 3D-printed bioactive glass for hypoxia-resistant photodynamic osteosarcoma therapy and bone regeneration.

Hong Cheng, Tao Wang, Hanji Huang, Tingting Hu, Fuzhi Pang, Jun Li, Yuxuan Zhao, Yuanyuan Liu, Simeng Yu, Pan Hu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hong ChengGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Collaborative Innovation Center of Regenerative Medicine and Medical Bioresource Development and Application Co-Constructed By the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.
Tao WangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, PR China.
Hanji HuangCenter of Reproductive Medicine, Birth Defects Prevention and Control Institute, Maternity and Child Health Care of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, 530021, PR China.
Tingting HuState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, PR China.
Fuzhi PangGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Collaborative Innovation Center of Regenerative Medicine and Medical Bioresource Development and Application Co-Constructed By the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.
Jun LiGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Collaborative Innovation Center of Regenerative Medicine and Medical Bioresource Development and Application Co-Constructed By the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.
Yuxuan ZhaoGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Collaborative Innovation Center of Regenerative Medicine and Medical Bioresource Development and Application Co-Constructed By the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.
Yuanyuan LiuInstitute of Life Science, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.
Simeng YuGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Collaborative Innovation Center of Regenerative Medicine and Medical Bioresource Development and Application Co-Constructed By the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.
Pan HuGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Collaborative Innovation Center of Regenerative Medicine and Medical Bioresource Development and Application Co-Constructed By the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.
Jinmin ZhaoGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Collaborative Innovation Center of Regenerative Medicine and Medical Bioresource Development and Application Co-Constructed By the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.
Li ZhengGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Collaborative Innovation Center of Regenerative Medicine and Medical Bioresource Development and Application Co-Constructed By the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.
Ruizheng LiangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, PR China.
Zhenhui LuGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Collaborative Innovation Center of Regenerative Medicine and Medical Bioresource Development and Application Co-Constructed By the Province and Ministry, Guangxi Key Laboratory of Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, Guangxi, 530021, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical management of osteosarcoma faces critical challenges, including postoperative recurrence and metastasis of residual tumor cells, chemotherapy resistance, and impaired self-repair capacity due to extensive bone defects following tumor resection. Herein, we develop a novel functionalized 3D-printed scaffold with NIR-II responsiveness (BGS/I-LDH@MgO

Indexed as

Hypoxia alleviationLayered double hydroxidesOsteogenesisOsteosarcomaPhotodynamic therapy

Identifiers

PMID42494752
PMCPMC13393564

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.