ArticleVeterinary world2026
Association of leptin and insulin-like growth factor-1 gene polymorphisms with milk production and reproductive traits in Indonesian Friesian Holstein cattle.
Article in Veterinary world, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Aim: Genetic polymorphisms in candidate genes associated with metabolic regulation and reproductive physiology are increasingly used to support marker-assisted selection in dairy cattle. Among these, leptin ( Materials and Methods: A total of 710 Friesian Holstein cows maintained at a commercial dairy farm in West Java, Indonesia, were used in this study. Genomic DNA was isolated from whole blood samples and genotyped using polymerase chain reaction-restriction fragment length polymorphism assays. Genotype and allele frequencies, polymorphic information content, and Hardy-Weinberg equilibrium were determined for each single nucleotide polymorphism. Associations between genotypes and productive traits, including days in milk, 305-day milk yield, total yield, average yield, and peak yield, as well as reproductive traits including calving interval, days open, first insemination postpartum, service per conception, and conception rate, were analyzed using mixed-effects models. Results: The Conclusion: The
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