Evidence map›Paper›PMID 42494120›Full record

ArticleMolecular plant pathology2026

FgCot1 Regulates Polarized Growth and Conidiation in Fusarium graminearum via Gpmk1 MAPK and Tsf1 Transcriptional Pathways.

Chengliang Li, Shaozhe Qin, Daiyuan Sun, Jingyi Ren, Cong Jiang, Jin-Rong Xu, Guanghui Wang

Abstract read
In one paragraph

Article in Molecular plant pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chengliang LiState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.
Shaozhe QinState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0009-0002-8017-1020
Daiyuan SunState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.
Jingyi RenState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.
Cong JiangState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.
Jin-Rong XuDepartment of Botany and Plant Pathology, Purdue University, West Lafayette, Indiana, USA.ORCID 0000-0001-5999-5004
Guanghui WangState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0002-8139-662X

Funding

National Key Research and Development Program of China 2022YFD1400100National Natural Science Foundation of China 32270209
6 · The paper itself

Abstract

Fusarium graminearum causes Fusarium head blight (FHB), a devastating wheat disease that threatens global food security and safety. Nuclear Dbf2-related (NDR) kinases regulate cellular morphogenesis, but their roles in phytopathogenic fungi remain elusive. Here, we characterized F. graminearum NDR kinase FgCot1, whose deletion severely disrupted vegetative growth, conidiation, polarized growth and pathogenicity. Notably, the Fgcot1 mutant showed genetic instability, producing fast-growing suppressors with primary (Gpmk1 pathway genes), secondary (MFS transporter SSF1) and tertiary (transcription factor TSF1) mutations. Functional analyses revealed that disrupting the Gpmk1 pathway partially rescued the Fgcot1 growth defects due to Gpmk1 hyperactivation, whereas SSF1 deletion independently enhanced growth. The TSF1

Indexed as

Fungal ProteinsFusariumSpores, FungalGene Expression Regulation, FungalMutationSignal TransductionTranscription FactorsTranscription, GeneticTriticumFungal ProteinsTranscription FactorsFusarium graminearumGpmk1 pathwayhomeobox transcriptional factorNDR kinasepolarized growthsuppressor mutations

Identifiers

PMID42494120
PMCPMC13396691

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.