Trial reportLasers in medical science2026
Effect of photobiomodulation on fatigue-related errors in ankle joint position reproduction: the moderating role of perceived ankle instability in a randomized, placebo-controlled trial.
Trial report in Lasers in medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate whether pre-exercise photobiomodulation (PBM) attenuates fatigue-induced decline in ankle joint position reproduction (JPR) and determine whether perceived ankle instability modifies this response. In this randomized, placebo-controlled trial with participant blinding and blinded outcome assessment, 30 healthy young adults (age: 24.3 ± 3.7 years; 15 male, 15 female) received either PBM or placebo treatment applied to the lower-leg musculature before a fatiguing protocol. PBM parameters included a wavelength of 830 nm, average power of 1 W, and total energy of 300 J per limb. Ankle JPR was assessed before and after fatigue. Participants were stratified by Cumberland Ankle Instability Tool (CAIT) scores. All physical assessments were performed by independent outcome assessors blinded to group allocation, with each participant evaluated by the same designated assessor throughout the study. The primary analysis revealed no overall between-group difference in fatigue-related changes in ankle JPR. A secondary exploratory group × CAIT interaction was observed, suggesting potential effect modification by perceived ankle instability. In the higher perceived instability subgroup, the estimated between-group difference was consistent with less post-fatigue worsening of JPR error following PBM; however, this estimate was based on small subgroup sizes and was not adjusted for multiple comparisons. The primary hypothesis was not supported; pre-exercise PBM showed no overall effect on fatigue-induced changes in ankle JPR. The exploratory group × CAIT interaction suggests that perceived ankle instability may be an effect modifier the response to PBM. However, this hypothesis requires confirmation in a larger, preregistered trial prospectively powered for interaction testing and incorporating functional outcomes in populations with clinically diagnosed chronic ankle instability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.