ArticleClinical oral investigations2026
Effect of dentin pre-treatment with Bioglass F18 suspensions on surface characteristics and bond strength of endodontic sealers.
Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo investigate whether dentin pre-treatment with bioactive glass F18 suspensions modifies dentin surface characteristics and influences the bond strength of bioceramic and epoxy resin-based endodontic sealers. MATERIAL AND
methodsExtracted human root canals were treated with distilled water, PBS or Bioglass F18 suspensions (2.5%, 5%, or 10%). Dentin surface morphology and elemental composition were analyzed by scanning electron microscopy and energy-dispersive X-ray spectroscopy. Bovine dentin specimens were treated with distilled water or 5% F18 and filled with a bioceramic (Bio-C Sealer) or epoxy resin-based sealer (AH Plus) for interfacial and mechanical analyses. The material-dentin interface was evaluated by micro-Fourier transform infrared spectroscopy after PBS immersion. Push-out and tensile bond strength tests were performed. Statistical analysis was performed using appropriate parametric or non-parametric tests according to data distribution. The level of significance was set at α = 0.05.
resultsBioglass F18 promoted the deposition of bioactive material on the dentin surface, with comparable effects observed at 5% and 10% concentrations. All F18 concentrations significantly increased the bond strength of both sealers compared with controls (p < 0.05). In tensile testing, dentin pre-treatment with 5% F18 resulted in significantly higher bond strength (p < 0.05). AH Plus exhibited higher bond strength than Bio-C Sealer in both mechanical tests (p < 0.05).
conclusionsDentin pre-treatment with Bioglass F18 enhanced dentin bioactivity and improved the sealer-dentin adhesion for both Bio-C Sealer and AH Plus. The effects were concentration-dependent across different outcomes, with 5% F18 showing favorable performance in tensile bond strength and comparable behavior to 10% F18 in push-out testing. CLINICAL RELEVANCE: Dentin pre-treatment with Bioglass F18 may improve sealer-dentin interfacial performance under in vitro conditions and could represent a potential adjunctive approach in root canal sealing strategies, pending further long-term and in vivo investigations.
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