Evidence map›Paper›PMID 42493329›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2026

Engagement and Outcomes Associated With Message-Based Psychotherapy Among Older and Younger Adults.

Brenna N Renn, Emily Peake, Lilla Brody, Aarthi Padmanabhan, Patrick J Raue

Abstract read
In one paragraph

Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brenna N RennDepartment of Psychology (BNR and LB), University of Nevada, Las Vegas, NV. Electronic address: brenna.renn@unlv.edu.
Emily PeakeTalkspace (EP and AP), New York, NY.
Lilla BrodyDepartment of Psychology (BNR and LB), University of Nevada, Las Vegas, NV.
Aarthi PadmanabhanTalkspace (EP and AP), New York, NY.
Patrick J RaueDepartment of Psychiatry & Behavioral Sciences (PJR), University of Washington, Seattle, WA.

Funding

Message-based psychotherapy and digital treatment sequences for depressionR44MH124334 · NIMH · TALKSPACE LLC · PI PADMANABHAN, AARTHI · 2020 to 2023
$3.9M
NIMH NIH HHS R44 MH124334
6 · The paper itself

Abstract

objectiveOlder adults are underrepresented in digital mental health research. As Medicare expands reimbursement for such services, understanding benefit is paramount. This study examined longitudinal engagement and clinical outcomes among older adults receiving virtual psychotherapy.

designRetrospective cohort study of patients who received usual psychotherapy care delivered as asynchronous message-based care and/or live tele-sessions.

settingTalkspace, a U.S. telemedicine platform.

participantsTalkspace users aged 65+ (n = 510) with elevated depression and/or anxiety symptoms and a randomly selected comparison sample of 510 adults 25-35 with similar depression/anxiety scores. MEASUREMENTS: Cohorts were compared across engagement with the platform and clinical outcomes (change in PHQ-9 [depressive symptoms] or GAD-7 [anxiety symptoms]) over 15 weeks.

resultsOlder adults engaged with the digital platform for a shorter duration than younger adults (mean [SD], 16.4 [26.6] versus 24.6 [31.6] weeks; t(989.45) = -4.45, p < 0.001) but did not differ in weekly message frequency, message word count, or video session attendance. Both groups showed significant reductions in depression and anxiety symptoms over 15 weeks. Among participants retained in treatment at week 15, 78.8% of older adults achieved at least the minimally important clinical difference for depression and 64.3% for anxiety, with corresponding rates of 50.0% and 53.7% among younger adults.

conclusionAdults aged 65 years and older engaged in digital psychotherapy at levels not significantly different from younger adults. Both older and younger groups experienced substantial reductions in depressive and anxiety symptoms and did not significantly differ in these improvements. Findings support feasibility and clinical utility for older adults.

Indexed as

anxietydepressionDigital mental healthtreatment

Identifiers

PMID42493329
PMCPMC13396683

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.