ArticleJournal of education and health promotion2026
QTc interval dynamics and heart rate variability response to submaximal exercise in normotensive young adults with and without parental hypertension.
Article in Journal of education and health promotion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProlonged QTc interval and reduced heart rate variability (HRV) are independent predictors of postexercise sudden cardiac death (SCD) in apparently healthy individuals. Offspring of hypertensive parents may exhibit early autonomic dysfunction, placing them at higher risk for future cardiovascular disease. This study evaluated the impact of submaximal aerobic exercise on QTc interval and its correlation with HRV in normotensive individuals with and without parental hypertension. MATERIALS AND
methodsA cross-sectional study was conducted on 100 healthy medical students (18-25 years), divided into normotensive offspring of hypertensive parents (NOHPs,
resultsFollowing exercise, NOHPs exhibited significantly prolonged QTc, higher LFnu, and elevated LF/HF ratio, alongside a reduction in HFnu compared with NONPs, indicating sympathovagal imbalance characterized by sympathetic predominance and vagal withdrawal. Correlation analysis revealed strong positive associations of QTc with LFnu and LF/HF ratio, and a negative association with HFnu in NOHPs during recovery.
conclusionSubmaximal exercise unmasks latent autonomic dysfunction in NOHPs, reflected as impaired vagal reactivation and augmented sympathetic drive, which is closely linked to prolonged QTc during recovery. The study highlights that combined QTc-HRV assessment, particularly after standardized exercise using the modified Bruce protocol, may serve as a sensitive early marker of repolarization instability and elevated arrhythmic risk in young individuals with genetic predisposition to hypertension.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.