Evidence map›Paper›PMID 42491965›Full record

ArticleActa ortopedica brasileira2026

PRP INFILTRATION

William Zarza Santos, Roberta Sessa Stilhano Yamaguchi, Edilson Silva Machado, Rodrigo Góes Medéa de Mendonça, Alberto Gotfryd, Robert Meves

Abstract read
In one paragraph

Article in Acta ortopedica brasileira, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William Zarza SantosIrmandade da Santa Casa de Misericordia de Sao Paulo, Departamento de Ortopedia e Traumatologia, Grupo de Afeccoes da Coluna Vertebral, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-9100-4749
Roberta Sessa Stilhano YamaguchiIrmandade da Santa Casa de Misericordia de Sao Paulo, Departamento de Ortopedia e Traumatologia, Grupo de Afeccoes da Coluna Vertebral, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-0653-5968
Edilson Silva MachadoIrmandade da Santa Casa de Misericordia de Sao Paulo, Departamento de Ortopedia e Traumatologia, Grupo de Afeccoes da Coluna Vertebral, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-0332-572X
Rodrigo Góes Medéa de MendonçaIrmandade da Santa Casa de Misericordia de Sao Paulo, Departamento de Ortopedia e Traumatologia, Grupo de Afeccoes da Coluna Vertebral, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-6118-9826
Alberto GotfrydIrmandade da Santa Casa de Misericordia de Sao Paulo, Departamento de Ortopedia e Traumatologia, Grupo de Afeccoes da Coluna Vertebral, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-3143-2845
Robert MevesIrmandade da Santa Casa de Misericordia de Sao Paulo, Departamento de Ortopedia e Traumatologia, Grupo de Afeccoes da Coluna Vertebral, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-8695-3982

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic low back pain is one of the most prevalent health conditions, with significant social and economic impact. Its increasing incidence has driven the demand for new, effective therapeutic alternatives. This study compared the efficacy of platelet-rich plasma (PRP) and corticosteroid injections in the treatment of chronic low back pain of facet joint origin. Methods: This was a randomized clinical trial involving patients with chronic low back pain of facet joint origin, selected through a positive response to medial branch block. Epidemiological data and clinical outcomes were analyzed, including disability questionnaires (Roland-Morris Disability Questionnaire) and the visual analog scale (VAS) for pain. Assessments were conducted at baseline, one month, and three months post-procedure. Results: A total of 59 patients were included, with 32 in the corticosteroid group and 27 in the PRP group. No significant differences were found between the treatments in terms of disability scores or the Roland-Morris Questionnaire. However, a significant interaction between treatment and time was observed (p = 0.038). Regarding pain scores, no significant differences were found between groups at any of the assessed time points. Conclusion: The study found no evidence of superiority of platelet-rich plasma over corticosteroid injections in terms of pain reduction and functional outcomes for the treatment of lumbar facet syndrome.

Indexed as

Adrenal Cortex HormonesInjectionsLow Back PainPlatelet-Rich Plasma

Identifiers

PMID42491965
PMCPMC13378704

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.