Evidence map›Paper›PMID 42491801›Full record

ArticleiScience2026

Automation and validation of an NMR spectroscopy-based drug discovery assay.

Thomas L Allam, Matthew Rice, Jose Ortega-Roldan, Jens Unger, Perry Hailey, Dominick Balderston, Kira Hilton, Olivia Keers, Pinky Naicker, Precious Popoola and 6 more

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Thomas L AllamUniversity of Southampton, School of Chemistry and Chemical Engineering, Southampton SO17 1BJ, UK.
Matthew RiceUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Jose Ortega-RoldanUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Jens UngerSplashlake, Robert-Bosch-Straße 7, 64293 Darmstadt, Germany.
Perry HaileyUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Dominick BalderstonUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Kira HiltonUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Olivia KeersUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Pinky NaickerUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Precious PopoolaUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Mackenzie StevensUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Lisa-Jane WhiteUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Burkhard SchäferSplashlake, Robert-Bosch-Straße 7, 64293 Darmstadt, Germany.
Jennifer R HiscockUniversity of Kent, School of Natural Sciences, Canterbury CT2 7NZ, UK.
Samantha Pearman-KanzaUniversity of Southampton, School of Chemistry and Chemical Engineering, Southampton SO17 1BJ, UK.
Jeremy FreyUniversity of Southampton, School of Chemistry and Chemical Engineering, Southampton SO17 1BJ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The trillion-dollar drug development industry depends on high-quality data to guide decision making processes. Many drug candidates work by targeting specific biological sites within disease-causing cells, often entering via passive diffusion through the cell membrane(s). We have previously developed a solution-state

Indexed as

automationcomputationally accessible datadigitisationdrug developmentdrug discoveryhigh-throughputNMR spectroscopypharmaceutical developmentsearchable datasupramolecular chemistry

Identifiers

PMID42491801
PMCPMC13378353

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.