ArticleIranian journal of veterinary research2025
Efficacy of enoxacin and levofloxacin against
Article in Iranian journal of veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Theileriosis is a tick-borne disease that significantly hampers livestock industries in developing nations. Buparvaquone is the only available option for the management of theileriosis. On the other hand, drug use or organism evolution has led to the evolution of resistance over past twenty years. Treatment for theileriosis requires alternative therapeutic approaches. Aims: This work examined the in-vitro effectiveness of enoxacin and levofloxacin compounds against Methods: The schizont infected cell line was established from infected cattle blood. The inhibitory effects of both drugs were assessed on Results: Enoxacin and levofloxacin efficiently inhibited 50% of the infection at 1,71,723 µM and 10,084 µM, respectively. Levofloxacin showed encouraging results during the experiment. For enoxacin and levofloxacin, the 50% cytotoxic effects were also measured at 10,529 µM and 10,116 µM, respectively. Enoxacin was safe on bovine red blood cells with an HC Conclusion: Levofloxacin showed satisfactory results compared to enoxacin. Further study is required along with other parameters to evaluate and assess the inhibitory activity of enoxacin and levofloxacin.
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