Evidence map›Paper›PMID 42491765›Full record

ArticleIranian journal of veterinary research2025

Glabridin ameliorates oxidative stress and inflammation in a bovine intestinal cell line and a colitis mouse model.

Y An, J Lu, X Wang, C Zhang, Sh Wang, Y Ma, Y Qiu, Sh Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Y AnMSc Student in Animal Nutrition, Henan International Joint Laboratory of Animal Welfare and Health Breeding, Faculty of Animal Nutrition, Henan University of Science and Technology, Luoyang, 471023, China.
J LuMSc Student in Animal Nutrition, Henan International Joint Laboratory of Animal Welfare and Health Breeding, Faculty of Animal Nutrition, Henan University of Science and Technology, Luoyang, 471023, China.
X WangHenan International Joint Laboratory of Animal Welfare and Health Breeding, Faculty of Animal Nutrition, Henan University of Science and Technology, Luoyang, 471023, China.
C ZhangHenan International Joint Laboratory of Animal Welfare and Health Breeding, Faculty of Animal Nutrition, Henan University of Science and Technology, Luoyang, 471023, China.
Sh WangHenan International Joint Laboratory of Animal Welfare and Health Breeding, Faculty of Animal Nutrition, Henan University of Science and Technology, Luoyang, 471023, China.
Y MaHenan International Joint Laboratory of Animal Welfare and Health Breeding, Faculty of Animal Nutrition, Henan University of Science and Technology, Luoyang, 471023, China.
Y QiuHenan International Joint Laboratory of Animal Welfare and Health Breeding, Faculty of Animal Nutrition, Henan University of Science and Technology, Luoyang, 471023, China.
Sh GuoHenan International Joint Laboratory of Animal Welfare and Health Breeding, Faculty of Animal Nutrition, Henan University of Science and Technology, Luoyang, 471023, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Oxidative stress (OS) adversely affects the intestinal health and mucosal barrier function in dairy cows. Glabridin (Glab), a natural flavonoid derived from licorice, has been shown to mitigate stress-related damage due to its antioxidant properties. Aims: This study aims to assess the impact of Glab on OS-induced damage in the bovine immortalized cell line (BIECs-21), validate its effectiveness Methods: The Results: Glab improved cell viability, reduced LDH release, and mitigated the adverse effects of H Conclusion: Glab reduces OS-induced apoptosis

Indexed as

AntioxidantApoptosisGlabridinInflammationOxidative stress

Identifiers

PMID42491765
PMCPMC13378044

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.