ArticleFrontiers in pediatrics2026
Quantifying knee cartilage development trajectories in children aged 6-12 years via diffusion tensor imaging.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: This study aims to establish normative diffusion tensor imaging (DTI) biomarkers of pediatric knee cartilage development trajectories and sex-specific differences by quantifying microstructural changes in children aged 6-12 years. Methods: Eighty-four healthy children (43 boys and 41 girls; mean age 9.01 ± 1.84 years) underwent 3.0T MRI of the left knee, including DTI sequences ( Results: FA values increased significantly with age and bone age ( Conclusion: DTI biomarkers (FA/ADC) sensitively reflect pediatric knee cartilage maturation, correlate best with bone age, and enhance quantitative monitoring of cartilage development and pathology in children.
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