Evidence map›Paper›PMID 42491518›Full record

ArticleEJVES vascular forum2026

Early Outcomes of Zone 2 Thoracic Endovascular Aortic Repair with an Integrated Branch Stent Graft for the Left Subclavian Artery: Evidence from a Western Centre.

Antonio Marzano, Claudia Bittoni, Francesca Miceli, Marta Ascione, Luca di Marzo, Wassim Mansour

Abstract read
In one paragraph

Article in EJVES vascular forum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antonio MarzanoVascular Surgery Unit, Department of General Surgery, Surgical Specialties and Anesthesiology, "Sapienza" University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Claudia BittoniVascular Surgery Unit, Department of General Surgery, Surgical Specialties and Anesthesiology, "Sapienza" University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Francesca MiceliVascular Surgery Unit, Department of General Surgery, Surgical Specialties and Anesthesiology, "Sapienza" University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Marta AscioneVascular Surgery Unit, Department of General Surgery, Surgical Specialties and Anesthesiology, "Sapienza" University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Luca di MarzoVascular Surgery Unit, Department of General Surgery, Surgical Specialties and Anesthesiology, "Sapienza" University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Wassim MansourVascular Surgery Unit, Department of General Surgery, Surgical Specialties and Anesthesiology, "Sapienza" University of Rome, Viale del Policlinico 155, Rome 00161, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Thoracic endovascular aortic repair (TEVAR) is widely used for thoracic aortic diseases, most commonly with a proximal landing in Ishimaru zone 3. When an adequate proximal sealing zone is lacking, extension into zone 2 is required, often necessitating left subclavian artery (LSA) revascularisation. The Castor single branched stent graft provides a fully endovascular solution for zone 2 TEVAR by incorporating an antegrade branch for the LSA. This study reports a single centre Western experience with this device. Method: A retrospective analysis was conducted on 15 consecutive patients undergoing elective zone 2 TEVAR with the Castor single branched stent graft between July 2023 and December 2025. Indications included thoracic aortic aneurysm, subacute or chronic Stanford type B dissection, and penetrating aortic ulcer. The primary endpoint was technical success, defined as accurate deployment without type I or III endoleak and with preserved LSA patency. Secondary endpoints included clinical success, access related complications, intensive care unit (ICU) and hospital stays, re-intervention, and death. Follow up consisted of serial computed tomography angiography. Results: The mean age was 63.9 ± 11 years, and 87% of patients were men. Technical and clinical success were achieved in 14 patients (93%). One patient required adjunctive covered stenting of the LSA for incomplete branch expansion. There were no access related complications or 30 day deaths. Mean ICU and hospital stays were 1.2 ± 0.6 days and 15.3 ± 9.6 days, respectively. Over a mean follow up of 13.5 ± 8.4 months, all LSA branches remained patent, with no endoleak, device migration, or re-intervention. Conclusion: Zone 2 TEVAR using the Castor single branched stent graft appears feasible, safe, and effective in a Western population. In this small elective series, LSA branch patency was maintained and no device related re-intervention occurred during available follow up. Larger studies with longer follow up are needed to assess durability and longer term outcomes.

Indexed as

Aortic arch pathologiesCastor branched endograftCastor stent graftThoracic endovascular aortic repair (TEVAR)Zone 2 aortic arch

Identifiers

PMID42491518
PMCPMC13377145

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.