ArticleiMeta2026
A spatiotemporal single-cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication.
Article in iMeta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Single-Cell Omics Advances in Understanding Tissue Development and Complex Trait Formation in Sheep and Goats.Animals : an open access journal from MDPI · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systematic characterization of cellular gene expression in livestock tissues during development is essential for understanding the regulation of complex traits. Despite the comprehensive profiling of cell atlases in livestock, a dynamic view of tissue development remains lacking. Here, using both single-cell and single-nucleus RNA sequencing, we present a comprehensive single-cell transcriptomic landscape of 252,033 cells/nuclei, mapping 83 distinct cell types across five pig tissues from prenatal to postnatal developmental stages. Our findings highlight the coordinated remodeling of tissue architecture through stem/progenitor cell proliferation, lineage specification, and functional maturation during organogenesis. We identified key transcription factors and regulatory networks that drive lineage-specific and spatiotemporally dynamic transcriptional programs. Developmental trajectory analysis identified a conserved bifurcated transcriptional organization of immune cells, accompanied by dynamic changes in transcription factors associated with immune cell maturation. Integrative analysis utilizing multi-omic, single-cell, and pig population genomics data identified a muscle-specific enhancer of the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.