Comprehensive Health Risk Assessment of Electronic Cigarette Aerosols: Metal and PAH Characterization, Oxidative Potential, and Cancer Risk Estimation.

Li-Ti Chou, Tsai-Ling Chen, Jen-Kun Chen, Hsiao-Chi Chuang, Kai-Chien Yang, Ta-Chih Hsiao

Abstract read

In one paragraph

Article in ACS environmental Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Li-Ti ChouGraduate Institute of Environmental Engineering, National Taiwan University, Taipei 106319, Taiwan.

Tsai-Ling ChenGraduate Institute of Environmental Engineering, National Taiwan University, Taipei 106319, Taiwan.

Jen-Kun ChenInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli 350401, Taiwan.ORCID https://orcid.org/0000-0002-3433-5971

Hsiao-Chi ChuangSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.

Kai-Chien YangDepartment and Graduate Institute of Pharmacology, National Taiwan University College of Medicine, Taipei 106319, Taiwan.

Ta-Chih HsiaoGraduate Institute of Environmental Engineering, National Taiwan University, Taipei 106319, Taiwan.ORCID https://orcid.org/0000-0003-4103-6272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electronic cigarettes (ECs) have emerged as popular alternatives to traditional cigarettes (TCs), yet their health impacts remain contentious due to limited systematic evaluations integrating multiple toxicological end points. This study provides a comprehensive assessment of EC aerosol toxicity by combining chemical characterization, oxidative potential (OP) measurement, and health risk modeling with systematic cross-study comparisons. Chemical analysis revealed that five metals (Cu, Ni, Ag, Zn, and Pb) originate exclusively from device components, while cross-study comparison identified substantial heterogeneity in metal profiles across different devices and studies. PAH analysis detected 14 compounds with a total concentration of 1.373 ng/puff. OP measurements demonstrated a marked dichotomy between OPv (49.87 nmol/min/m

Indexed as

electronic cigarettes (ECs)excess lifetime cancer risk (ELCR)inhalation risk assessmentoxidative potential (OP)particle size distribution (PSD)polycyclic aromatic hydrocarbons (PAHs)

Identifiers

PMID42491501

DOI10.1021/acsenvironau.5c00304

PMCPMC13377506

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.