Evidence map›Paper›PMID 42491437›Full record

ReviewJAC-antimicrobial resistance2026

Antimicrobial stewardship in UK special care baby units: gaps in research and future directions.

Amedine Duret, Frances Davies, Felicity Fitzgerald, Mark Gilchrist, Charlene Rodrigues, Jayanta Banerjee, Vijaykumar Shivamurthappa, Aisleen Bennett

Abstract readReview
In one paragraph

Review in JAC-antimicrobial resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amedine DuretSection of Paediatric Infectious Diseases, Department of Infection, Imperial College London, London, UK.
Frances DaviesDepartment of Microbiology, Imperial College Healthcare NHS Trust, London, UK.ORCID https://orcid.org/0000-0003-1839-870X
Felicity FitzgeraldSection of Paediatric Infectious Diseases, Department of Infection, Imperial College London, London, UK.ORCID https://orcid.org/0000-0001-9594-3228
Mark GilchristDepartment of Infectious Diseases, Imperial College Healthcare NHS Trust, London, UK.ORCID https://orcid.org/0009-0003-0625-3535
Charlene RodriguesDepartment of Paediatric Infectious Diseases, Imperial College Healthcare NHS Trust, London, UK.
Jayanta BanerjeeDepartment of Neonatology, Imperial College Healthcare NHS Trust, London, UK.
Vijaykumar ShivamurthappaDepartment of Neonatology, Imperial College Healthcare NHS Trust, London, UK.
Aisleen BennettSection of Paediatric Infectious Diseases, Department of Infection, Imperial College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite a significant decline in the incidence of neonatal sepsis, the clinical imperative to avoid missing life-threatening infection continues to drive widespread antibiotic overprescription. Antimicrobial stewardship is universally recognized and explicitly mandated within the UK 2024-2029 National Action Plan on Antimicrobial Resistance as a critical mechanism to combat resistance and prevent iatrogenic harms related to infant dysbiosis. However, a major misalignment exists within the current evidence base: most of the neonatal stewardship research is conducted in highly resourced, tertiary Neonatal Intensive Care Units (Level 3), even though most postnatal inpatient care occurs in Special Care Baby Units (Level 1) and Local Neonatal Units (Level 2). This Viewpoint explores the operational and structural barriers that limit the transferability of intensive-care stewardship models to lower-acuity settings, identifies key research gaps around baseline prescribing practices and multidisciplinary collaboration, and argues for the inclusion of Level 1 and 2 populations in future validation studies of emerging diagnostic tools for neonatal sepsis.

Identifiers

PMID42491437
PMCPMC13376670

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.