ArticleRSC advances2026
M-NGO/UiO-66 nanocomposite: a green and efficient catalyst for the synthesis of 1,8-dioxodecahydroacridine derivatives.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In this study, a novel magnetic nanocomposite (M-NGO/UiO-66) was successfully synthesized. This nanocomposite was utilized as a green, heterogeneous, and recoverable catalyst in a one-pot pseudo-four-component reaction for the preparation of 1,8-dioxodecahydroacridine derivatives. The structure and physicochemical properties of the resulting nanocomposite were thoroughly characterized and confirmed using FT-IR, XRD, SEM, EDS, elemental mapping, BET, and VSM techniques. The catalytic performance of M-NGO/UiO-66 was evaluated under optimized reaction conditions, including 0.015 g of catalyst in ethanol at 80 °C, affording the target products within 8-25 min and in high yields ranging from 83% to 95%. The developed protocol demonstrates several significant advantages, such as operational simplicity, excellent catalytic activity, high atom economy, favorable reaction mass efficiency, utilization of a green solvent, and convenient magnetic recovery of the catalyst, making it an attractive and sustainable approach for the synthesis of acridine derivatives.
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