Evidence map›Paper›PMID 42491386›Full record

ReviewCureus2026

Role of Vigorous Physical Activity in Mental Health: A Narrative Review.

Konstantinos Stratakis, Jovana Todorovic, Zorica Terzić Šupić

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Konstantinos StratakisInstitute of Medical Physiology, Faculty of Medicine, University of Belgrade, Belgrade, SRB.
Jovana TodorovicInstitute of Social Medicine, Faculty of Medicine, University of Belgrade, Belgrade, SRB.
Zorica Terzić ŠupićInstitute of Social Medicine, Faculty of Medicine, University of Belgrade, Belgrade, SRB.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity (PA) is widely associated with favorable mental health outcomes. However, much of the literature has examined PA as a broad exposure, usually in terms of total volume, participation status, or combined moderate-to-vigorous PA. This approach may neglect the potential importance of activity intensity. Vigorous physical activity (VPA) differs from lower-intensity activity in physiological demands, subjective effort, affective responses, and behavioral contexts and may, therefore, represent a distinct dimension of PA behavior. This narrative review aims to examine whether VPA should be considered a distinct dimension of PA behavior in mental health research by synthesizing mechanistic rationale, intervention evidence, and observational findings, while clarifying how differences in VPA definition, measurement approach, study design, population, and outcome selection contribute to inconsistent findings across the literature. The available evidence suggests that VPA is relevant to mental health, although the strength of evidence differs across outcomes. Findings are most developed for depressive symptoms, where both intervention and observational studies generally support favorable associations. Structured VPA may reduce depressive symptoms in some populations, while habitual VPA has been associated with lower depressive symptom burden in observational research. Evidence for other outcomes, including anxiety, perceived stress, psychological distress, sleep quality, and mental well-being, is more limited but suggests that the relevance of VPA may extend beyond depression alone. However, these findings remain less directly comparable because studies differ in outcome measures, populations, and study designs. Interpretation is complicated by the inconsistent definition of VPA across the literature. Prescribed VPA, habitual VPA, frequency of VPA, and the proportion of VPA within total PA are related but distinct constructs. High-intensity interval training is also a relevant, structured form of VPA, but it should not be treated as equivalent to all forms of VPA. These definitional differences, together with variation in measurement methods, populations, and mental health outcomes, help explain why findings remain inconsistent. Overall, VPA deserves consideration as a distinct feature of PA behavior in mental health research. Future studies should define VPA more precisely, distinguish absolute from proportion-based measures, account for total PA volume, and examine specific mental health outcomes separately.

Indexed as

anxietydepressive symptomshigh-intensity interval trainingmental healthmental well-beingperceived stressphysical activitypsychological distressvigorous physical activity

Identifiers

PMID42491386
PMCPMC13377132

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.