ArticleFrontiers in cardiovascular medicine2026
Predictive value of left atrial diameter and epicardial adipose tissue in sleep apnea and heart failure with preserved ejection fraction.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aims to investigate the association of left atrial diameter (LAD) and epicardial adipose tissue (EAT) with heart failure with preserved ejection fraction (HFpEF) in patients with sleep apnea (SA) and to evaluate their potential as markers for risk stratification. Methods: A total of 170 hospitalized patients with SA, diagnosed by polysomnography and who underwent cardiac CT between July 2022 and June 2023, were enrolled. Participants were divided into an HFpEF group ( Results: Patients with HFpEF had significantly higher LAD, apnea-hypopnea index, EAT relative volume, and NT-proBNP levels than those without HFpEF (all Conclusion: LAD was positively correlated with EAT relative volume, AHI, and NT-proBNP levels. Both LAD and EAT relative volume were significantly associated with HFpEF in SA patients and may serve as potential markers for identifying high-risk individuals.
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