Evidence map›Paper›PMID 42491218›Full record

ArticleAmerican journal of translational research2026

Application of high-frequency musculoskeletal ultrasound combined with shear wave elastography in assessing paravertebral muscle morphology in adolescents with idiopathic scoliosis.

Binbin Ruan, Zhikai Ni, Hongyan Xie, Junsong Tian, Muni Chen, Xiaobo Yang, Bin Wu, Xiang Zhang, Jing Zhang

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Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Binbin RuanDepartment of Ultrasound, Yuyao Traditional Chinese Medicine Hospital No. 1500 South Zhongshan Road, Yuyao 315400, Zhejiang, China.
Zhikai NiSchool of Medicine, Xiamen University No. 4221 South Xiang'an Road, Xiang'an District, Xiamen 361000, Fujian, China.
Hongyan XieDepartment of Ultrasound, Yuyao Traditional Chinese Medicine Hospital No. 1500 South Zhongshan Road, Yuyao 315400, Zhejiang, China.
Junsong TianDepartment of Acupuncture and Tuina Rehabilitation, Yuyao Traditional Chinese Medicine Hospital No. 1500 South Zhongshan Road, Yuyao 315400, Zhejiang, China.
Muni ChenDepartment of Ultrasound, Yuyao Traditional Chinese Medicine Hospital No. 1500 South Zhongshan Road, Yuyao 315400, Zhejiang, China.
Xiaobo YangDepartment of Ultrasound, Yuyao Traditional Chinese Medicine Hospital No. 1500 South Zhongshan Road, Yuyao 315400, Zhejiang, China.
Bin WuDepartment of Ultrasound, Yuyao Traditional Chinese Medicine Hospital No. 1500 South Zhongshan Road, Yuyao 315400, Zhejiang, China.
Xiang ZhangSchool of Medicine, Shanghai University Shanghai 200444, China.
Jing ZhangDepartment of Ultrasound, Yuyao Traditional Chinese Medicine Hospital No. 1500 South Zhongshan Road, Yuyao 315400, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the clinical utility of high-frequency musculoskeletal ultrasound combined with shear wave elastography (SWE) in assessing paravertebral muscle asymmetry in adolescents with adolescent idiopathic scoliosis (AIS), and to investigate its relationship with Cobb angle across different body positions.

methodsA total of 100 adolescents with AIS (mean age: 12.81 ± 1.86 years) were included. Ultrasound examinations were performed at the upper, apex, and lower vertebrae in both standing and prone positions using ALOKA ARIETTA 60 and 850 systems. Muscle parameters (transverse diameter, anteroposterior diameter, circumference, and area) and SWE values were measured. Differences between concave and convex sides were analyzed, and correlations with Cobb angle were assessed using SPSS 27.0 and R 4.3.1.

resultsSignificant asymmetry in paravertebral muscle parameters was observed at all vertebral levels, particularly at the apex (P<0.05). SWE demonstrated significantly higher muscle stiffness on the concave side (P<0.05). Stronger correlations between muscle asymmetry and Cobb angle were found in the standing position, with area showing the highest correlation coefficients. Compared with the prone position, standing measurements more accurately reflected scoliosis severity.

conclusionsHigh-frequency musculoskeletal ultrasound combined with SWE is an effective, non-invasive method for evaluating paravertebral muscle asymmetry in AIS. The standing position provides more clinically relevant information, and muscle asymmetry is strongly associated with Cobb angle. This technique may support improved diagnosis, monitoring, and individualized treatment planning in AIS.

Indexed as

adolescent idiopathic scoliosisCobb angleHigh-frequency musculoskeletal ultrasoundmuscle asymmetryparavertebral musclesscoliosisshear wave elastography

Identifiers

PMID42491218
PMCPMC13376048

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.