Evidence map›Paper›PMID 42491126›Full record

ArticleFrontiers in public health2026

From symptom onset to care-seeking: a process-oriented mixed-methods study of prehospital delay in cerebral infarction.

Biao Xu, Zhi-Qiang Ge, Yi-Fan Shao, Cheng-Xiao Ma, Li Li

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Biao XuSchool of Government, Nanjing University, Nanjing, China.
Zhi-Qiang GeSchool of Government, Nanjing University, Nanjing, China.
Yi-Fan ShaoSchool of Government, Nanjing University, Nanjing, China.
Cheng-Xiao MaDepartment of Neurology, Nanjing Drum Tower Hospital, Nanjing, China.
Li LiDepartment of Neurology, Nanjing Drum Tower Hospital, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cerebral infarction (ischemic stroke) is a highly time-sensitive acute cerebrovascular event, yet prehospital delays in patients' accessing medical care remain prevalent across various countries and healthcare systems. Previous studies have primarily attributed delays to inadequate symptom recognition or barriers in healthcare accessibility, with limited systematic exploration of their formation mechanisms from a decision-making process perspective. Methods: This study integrated the Self-Regulation Model and the three-stage delay model, employing an explanatory sequential mixed-methods approach to examine the cognitive and decision-making processes among cerebral infarction patients who delayed seeking care. A total of 68 patients completed the Brief Illness Perception Questionnaire, and semi-structured interviews were conducted with 16 of these patients. Results: Findings indicate that delays in seeking medical care result from distinct mechanisms operating at different stages. During the appraisal delay stage, patients tended to normalize early or atypical symptoms. In the illness delay stage, optimism bias, self-regulatory overestimation, and doubts about medical efficacy reinforced a "wait-and-see" strategy. At the utilization delay stage, considerations of financial burden, family responsibilities, and societal role consequences significantly inhibited immediate healthcare-seeking behavior. Both quantitative and qualitative analyses revealed a cognitive-behavioral disconnect between illness perceptions and actual healthcare decisions. Conclusion: This study extends the explanatory power of Self-Regulation Model in healthcare decision-making contexts from a process-oriented perspective and offers a theoretical basis for designing staged, cognition-focused interventions aimed at reducing treatment delays.

Indexed as

Cerebral InfarctionPatient Acceptance of Health CareAgedDecision MakingFemaleHumansInterviews as TopicMaleMiddle AgedSurveys and QuestionnairesTreatment Delayhealth promotionillness perceptionmixed methodspatient delaystroke

Identifiers

PMID42491126
PMCPMC13376248

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.