Evidence map›Paper›PMID 42491106›Full record

ArticleAmerican journal of translational research2026

Construction and verification of an early warning model for hypothermia in emergency trauma patients based on the random forest method.

Jiawen Cao, Xu Mu, Huanqing Zhu, Yun Liu

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Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Jiawen CaoThe Second Clinical Medical College of Guizhou University of Traditional Chinese Medicine Guiyang 550003, Guizhou, China.
Xu MuEmergency Department, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine Guiyang 550003, Guizhou, China.
Huanqing ZhuThe Second Clinical Medical College of Guizhou University of Traditional Chinese Medicine Guiyang 550003, Guizhou, China.
Yun LiuEmergency Department, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine Guiyang 550003, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo construct an early warning model for hypothermia in emergency trauma patients using Random Forest (RF) and compare its predictive performance with Logistic regression.

methodsA total of 400 trauma patients were included. Hypothermia was defined as any temperature < 36.0°C within 3 hours after admission. Patients were randomly divided into training and test sets (7:3). Based on the data of the modeling set, the least absolute shrinkage and selection operator (LASSO) regression was used to identify the characteristic variables of hypothermia in patients. Logistic regression model and RF model are constructed based on the identified characteristic variables.

resultsAmong 400 patients, 92 (23.00%) developed hypothermia. The LASSO regression identified six non-zero coefficient indicators, including RTS score, ISS, SI index, ambient temperature at the time of injury, wet clothing, and shock upon entering the room. Based on these, a Logistic regression model and a RF model were constructed. The RF model achieved an AUC of 0.985 (95% CI: 0.972-0.997) in the training set and 0.956 (95% CI: 0.921-0.990) in the test set; the Logistic model achieved 0.963 (95% CI: 0.939-0.988) and 0.956 (95% CI: 0.923-0.989), respectively. Calibration curves demonstrated good agreement between predicted and observed outcomes. DCA revealed that the RF model provided higher standardized net benefit across a wider range of threshold probabilities.

conclusionThe RF-based early warning model demonstrates high predictive efficacy for hypothermia in emergency trauma patients and outperforms traditional Logistic regression, supporting early identification and preventive intervention.

Indexed as

early warning modelEmergency traumahypothermiamachine learningrandom forestrisk factors

Identifiers

PMID42491106
PMCPMC13376059

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.