Evidence map›Paper›PMID 42491046›Full record

ArticleFrontiers in immunology2026

Increased optic nerve-region [

Sebastian E Serfling, Marc Schmalzing, Yingjun Zhi, Patrick-Pascal Strunz, Hannah Labinsky, Philipp E Hartrampf, Andreas K Buck, Thorsten A Bley, Konstanze V Guggenberger, Rudolf A Werner and 1 more

Abstract read
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In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sebastian E SerflingDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Marc SchmalzingDepartment of Medicine II, Rheumatology and Clinical Immunology, University Hospital Würzburg, Würzburg, Germany.
Yingjun ZhiDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital, Würzburg, Germany.
Patrick-Pascal StrunzDepartment of Medicine II, Rheumatology and Clinical Immunology, University Hospital Würzburg, Würzburg, Germany.
Hannah LabinskyDepartment of Medicine II, Rheumatology and Clinical Immunology, University Hospital Würzburg, Würzburg, Germany.
Philipp E HartrampfDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Andreas K BuckDepartment of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
Thorsten A BleyDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.
Konstanze V GuggenbergerDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Würzburg, Würzburg, Germany.
Rudolf A WernerDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität (LMU) University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.
Michael GernertDepartment of Medicine II, Rheumatology and Clinical Immunology, University Hospital Würzburg, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are considered part of a shared disease spectrum. While orbital inflammatory changes have been described in GCA, the presence of increased optic nerve-region metabolic activity in PMR remains unclear. This study aimed to evaluate canalicular optic nerve-region [ Methods: In this retrospective single-center study, PMR patients (without signs and symptoms of GCA), who underwent [ Results: PMR patients ( Conclusion: Patients with clinically isolated PMR showed increased [

Indexed as

Fluorodeoxyglucose F18Giant Cell ArteritisOptic NervePolymyalgia RheumaticaPositron Emission Tomography Computed TomographyAgedAged, 80 and overFemaleHumansMaleMiddle AgedRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18Radiopharmaceuticals[18F]FDG PET/CTGCA-PMR spectrum diseasegiant cell arteritisoptic nerve-region uptakepolymyalgia rheumatica

Identifiers

PMID42491046
PMCPMC13375866

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.