Evidence map›Paper›PMID 42491033›Full record

ArticleAmerican journal of translational research2026

Flexible ureterorenoscopy with holmium laser lithotripsy for ureteral calculi complicated by hydronephrosis.

Junjie Zhi, Hao Lin, Xiang Zhang, Yifan Sun, Peng Jiang, Ninghan Feng

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Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Junjie ZhiDepartment of Urology, Wuxi No. 2 Hospital, Nanjing Medical University Wuxi 214000, Jiangsu, China.
Hao LinDepartment of Urology, Jiangnan University Medical Center Wuxi 214000, Jiangsu, China.
Xiang ZhangDepartment of Urology, Jiangnan University Medical Center Wuxi 214000, Jiangsu, China.
Yifan SunDepartment of Urology, Jiangnan University Medical Center Wuxi 214000, Jiangsu, China.
Peng JiangDepartment of Urology, Jiangnan University Medical Center Wuxi 214000, Jiangsu, China.
Ninghan FengDepartment of Urology, Wuxi No. 2 Hospital, Nanjing Medical University Wuxi 214000, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo clarify the effects of flexible ureterorenoscopy (FURS) combined with holmium laser lithotripsy on surgical outcomes, postoperative pain (POP), and renal function (RF) for the treatment of ureteral calculi (UC) complicated by hydronephrosis (HN).

methodsA total of 128 patients diagnosed with UC complicated with HN treated between February 2024 and December 2025 were enrolled in this retrospective study and divided according to surgical approach. Among them, 65 patients underwent FURS combined with holmium laser lithotripsy (FURS group), and 63 patients received conventional ureteroscopy (URS) combined with laser lithotripsy (URS group). The two groups were compared in terms of clinical efficacy, surgical metrics (intraoperative blood loss, operative time, one-time stone clearance success rate), hospitalization indicators (hospitalization duration and medical expenses), POP, renal function, routine urine test results, serum inflammatory markers, and postoperative complications.

resultsThe FURS group exhibited a significantly higher overall treatment efficacy rate (P=0.035). Additionally, the FURS group had less intraoperative blood loss, a shorter operative time, and a shorter hospital stay (all P<0.001). In terms of postoperative recovery, patients in the FURS group experienced milder pain on postoperative days 1 (P=0.032) and 3 (P<0.001), with better preserved postoperative renal function (P<0.05), improved routine urine test indicators (P<0.05), lower serum inflammatory levels (P<0.05), and fewer total complications (P<0.001). No significant differences were observed between the two groups in the one-time stone clearance success rate and hospitalization expenses (all P>0.05).

conclusionFURS demonstrated significantly superior clinical efficacy to conventional URS for the treatment of UC complicated by HN, with better surgical outcome and more safety.

Indexed as

flexible ureterorenoscopy combined with holmium laser lithotripsyhydronephrosispostoperative painrenal functionsurgical metricsUreteral calculiureteroscopy with laser lithotripsy

Identifiers

PMID42491033
PMCPMC13376012

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.