ArticlePhysics and imaging in radiation oncology2026
A framework for planning organ at risk volume margin derivation for the small bowel during magnetic resonance-guided radiotherapy.
Article in Physics and imaging in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Purpose: The small bowel is highly radiosensitive and prone to motion during abdominal and pelvic radiotherapy, risking overdosage. This study extended a previously presented small bowel tracking framework to enable automated planning organ at risk volume (PRV) margin derivation. Materials and Methods: MR scans were obtained in 18 patients treated for abdominal lesions, with abdominal compression. The mean motion, maximum displacement and position of the small bowel during the acquisition (7.5 min) were determined. The position of the small bowel over time was used to derive PRV margins based on geometrical coverage. Results: Displacements Conclusions: While the small bowel can undergo considerable intrafraction displacements during treatment, most of this motion can be effectively encompassed using a moderate intrafraction PRV margin for this specific cohort. This study presents an automated framework to derive patient- and treatment-specific margins, directly from bowel tracking data, enabling tailored coverage-based margins.
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