Evidence map›Paper›PMID 42491006›Full record

ReviewGenes & diseases2026

DNA-based vaccines: Advances, applications, and future prospects.

Zhichang Peter Zhou, Ziyan Rachel Chen, Ranmal Avinash Bandara, Rongqi Duan, Huibi Cao, Jun Liu, Jim Hu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Genes & diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhichang Peter ZhouTranslational Medicine Program, Hospital for Sick Children Research Institute, Toronto, Ontario M5G 0A4, Canada.
Ziyan Rachel ChenTranslational Medicine Program, Hospital for Sick Children Research Institute, Toronto, Ontario M5G 0A4, Canada.
Ranmal Avinash BandaraTranslational Medicine Program, Hospital for Sick Children Research Institute, Toronto, Ontario M5G 0A4, Canada.
Rongqi DuanDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Huibi CaoDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Jun LiuDepartment of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Jim HuTranslational Medicine Program, Hospital for Sick Children Research Institute, Toronto, Ontario M5G 0A4, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA-based vaccines represent a promising advancement in immunization strategies, offering a novel approach for preventing infectious diseases and treating various conditions, including cancers and autoimmune disorders. These vaccines utilize genetically engineered plasmid or viral vector DNA encoding antigens of interest, which, upon administration, are taken up by host cells to produce the antigen

Indexed as

DNA vaccinesImmunotherapyInfectious diseasesPandemicPlasmidsViral vectors

Identifiers

PMID42491006
PMCPMC13375960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.