Evidence map›Paper›PMID 42490838›Full record

ArticleJournal of medical cases2026

Emergency Laparoscopic Appendectomy in a High-Risk Cardiac Patient With Severe Left Main Coronary Artery Disease on Dual Antiplatelet Therapy.

Blerim Arapi, Alma Cani, Rudin Domi, Gentian Huti, Asead Abdyli, Krenar Lilaj, Filadelfo Coniglione, Mustafa Bajraktari, Rinard Kortoci, Majlinda Naco and 4 more

Abstract readCase Reports
In one paragraph

Article in Journal of medical cases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Blerim ArapiDepartment of Anesthesia and Intensive Care, Hygeia International Hospital, Tirana, Albania.
Alma CaniDepartment of Surgery, University of Medicine, Tirana, Albania.
Rudin DomiDepartment of Surgery, University of Medicine, Tirana, Albania.
Gentian HutiDepartment of Anesthesia and Intensive Care, American Hospital 3, Tirana, Albania.
Asead AbdyliDepartment of Anesthesia and Intensive Care, American Hospital 3, Tirana, Albania.
Krenar LilajDepartment of Surgery, University of Medicine, Tirana, Albania.
Filadelfo ConiglioneDepartment of Clinical Science and Translational Medicine, Tor Vergata University of Rome, Rome, Italy.
Mustafa BajraktariDepartment of Anesthesia and Intensive Care, American Hospital 2, Tirana, Albania.
Rinard KortociDepartment of Anesthesia and Intensive Care, American Hospital 2, Tirana, Albania.
Majlinda NacoDepartment of Surgery, University of Medicine, Tirana, Albania.
Arjana SinaImaging Service, Wellness Albania Clinic, Tirana, Albania.
Migena VarguDepartment of Infectious Diseases, University of Medicine, Tirana, Albania.
Ergita NelajDepartment of Internal Medicine, University of Medicine, Tirana, Albania.
Vedat EljeziDepartment of Perioperative Medicine, CHU Gabriel-Montpied, Clermont-Ferrand, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emergency noncardiac surgery in patients with advanced coronary artery disease and recent coronary stent implantation poses a substantial anesthetic challenge. Clinicians must carefully balance the heightened risk of perioperative bleeding associated with continued dual antiplatelet therapy against the potentially catastrophic risk of stent thrombosis if such therapy is interrupted. We described the perioperative management of a 68-year-old man with severe multivessel coronary artery disease, critical left main stenosis, impaired left ventricular function, and recent coronary stenting, who required emergency laparoscopic appendectomy for perforated appendicitis. General anesthesia was administered with comprehensive invasive hemodynamic monitoring and tailored vasopressor support. The procedure was completed successfully, and the postoperative course was uneventful. This case underscored the feasibility of proceeding with emergency laparoscopic abdominal surgery without interruption of dual antiplatelet therapy in a patient with high-risk coronary anatomy, including left main disease. It highlighted a pragmatic, individualized anesthetic strategy integrating advanced hemodynamic monitoring, goal-directed support, and close multidisciplinary coordination, offering practical insight into managing the competing risks of bleeding and stent thrombosis in time-critical surgical settings.

Indexed as

AnesthesiaCoronary artery diseaseCoronary stentsDual antiplatelet therapyEmergent surgery

Identifiers

PMID42490838
PMCPMC13375436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.