ReviewAdvanced healthcare materials2026
Overview of Silk Fibroin Injectable Hydrogels: Advances and Applications in Regenerative Medicine.
Review in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Tissue repair following disease or injury remains a major clinical challenge, driving the search for advanced biomaterials that can effectively support tissue regeneration. Injectable hydrogels have recently gained significant attention as promising candidates in regenerative medicine due to their minimally invasive administration, ability to conform to irregular defects, and precise spatial localization, overcoming the limitations of conventional pre-formed hydrogels. Among natural polymers, silk fibroin (SF) has attracted considerable attention owing to its unique chemical structure, outstanding mechanical properties, versatile processability, biocompatibility, cost-effectiveness, and large-scale availability. Consequently, a wide variety of SF-based injectable hydrogels have been developed, either alone or in combination with other biomaterials, for diverse tissue engineering applications. This review provides an in-depth discussion of their injectability, underlying gelation mechanisms, and therapeutic advantages, including roles in tissue regeneration, drug delivery, cell therapy, immunomodulation, and angiogenesis. Furthermore, the current challenges, recent advances, and future directions for the clinical translation of SF-based injectable hydrogels are critically assessed, highlighting their potential as next-generation biomaterials for regenerative medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.