Evidence map›Paper›PMID 42490226›Full record

ArticleSTAR protocols2026

Protocol for high-density peptide and protein presentation on biomaterial surfaces using virus-like particles.

Rayane Hedna, Hasna Maayouf, Thomas Dos Santos, Laurent Pieuchot

Abstract read
In one paragraph

Article in STAR protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rayane HednaMulhouse Institute of Materials Science (IS2M), CNRS UMR 7361, University of Haute-Alsace, 68100 Mulhouse, France. Electronic address: rayane.hedna@uha.fr.
Hasna MaayoufMulhouse Institute of Materials Science (IS2M), CNRS UMR 7361, University of Haute-Alsace, 68100 Mulhouse, France.
Thomas Dos SantosMulhouse Institute of Materials Science (IS2M), CNRS UMR 7361, University of Haute-Alsace, 68100 Mulhouse, France.
Laurent PieuchotMulhouse Institute of Materials Science (IS2M), CNRS UMR 7361, University of Haute-Alsace, 68100 Mulhouse, France. Electronic address: laurent.pieuchot@uha.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we present a protocol for achieving high-density peptide and protein presentation on biomaterial surfaces using self-assembling virus-like particles. We describe steps for the design, recombinant production, purification, and quality control of peptide- or protein-displaying particles. We also detail procedures for their use in functionalizing polydimethylsiloxane (PDMS) and other solid substrates. The approach enables multivalent and spatially controlled ligand presentation and is applicable to reproducible cell-material interaction studies and the biofunctionalization of implant-relevant surfaces. For complete details on the use and execution of this protocol, please refer to Maayouf et al.

Indexed as

Biotechnology and bioengineeringCell cultureProtein expression and purification

Identifiers

PMID42490226
PMCPMC13425840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.