Evidence map›Paper›PMID 42490214›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2026

Role of ROS, soluble guanylate cyclase and cGMP in mouse lung development during hyperoxia.

My Linh Nguyen, Joann M Taylor, V Joseph Dudley, Gregory B Waypa, Paul T Schumacker

Abstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

My Linh NguyenDivision of Neonatology, Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States.
Joann M TaylorDivision of Neonatology, Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States.
V Joseph DudleyDivision of Neonatology, Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States.
Gregory B WaypaDivision of Neonatology, Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States.ORCID 0000-0002-6179-4209
Paul T SchumackerDivision of Neonatology, Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States.ORCID 0000-0001-9591-2034

Funding

Mechanism of transplanted neonatal cardiac progenitor cells to repair ischemic myocardiumR01HL118491 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI SCHUMACKER, PAUL T · 2014 to 2024
$4.4M
Redox Regulation of Vascular cGMP Signaling in Neonatal LungsR01HL109478 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHUMACKER, PAUL T · 2011 to 2020
$4.2M
HHS | National Institutes of Health (NIH) HL109478HHS National Institutes of Health (NIH) HL118491NHLBI NIH HHS R01 HL109478NHLBI NIH HHS R01 HL118491
6 · The paper itself

Abstract

Bronchopulmonary dysplasia (BPD) is characterized by disruption of newborn lung alveolar and vascular development. Administration of supplemental O

Indexed as

Cyclic GMPHyperoxiaLungReactive Oxygen SpeciesSoluble Guanylyl CyclaseAnimalsAnimals, NewbornAntioxidantsAzolesFemaleHEK293 CellsHumansIsoindolesMiceMice, Inbred C57BLMitochondriaAntioxidantsAzolesCyclic GMPebselenIsoindolesOrganoselenium CompoundsReactive Oxygen SpeciesSoluble Guanylyl Cyclasebronchopulmonary dysplasiahyperemiamitochondriareactive oxygen speciesredox signaling

Identifiers

PMID42490214
PMCPMC13555625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.