Evidence map›Paper›PMID 42489921›Full record

ArticleArchives of toxicology2026

No clear evidence of PFAS-induced immunomodulation in SARS-CoV-2-specific human T cell responses following vaccination.

Hermann-Josef Thierse, Katharina Sommerkorn, Moustapha Sy, Patrick Tarnow, Andreas Luch, Katherina Siewert

Abstract readLetter
In one paragraph

Article in Archives of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hermann-Josef ThierseDepartment of Chemicals and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany. Hermann-Josef.Thierse@bfr.bund.de.ORCID http://orcid.org/0000-0001-9655-681X
Katharina SommerkornDepartment Food and Feed Safety in the Food Chain, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
Moustapha SyDepartment of Chemicals and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.ORCID http://orcid.org/0000-0001-9461-7316
Patrick TarnowDepartment of Chemicals and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.ORCID http://orcid.org/0000-0002-9250-6775
Andreas LuchDepartment of Chemicals and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
Katherina SiewertDepartment of Chemicals and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.ORCID http://orcid.org/0000-0003-0380-1594

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antigen-specific T cell activationCD154COVID-19 vaccinationHuman peripheral blood mononuclear cells (PBMC)Per- and polyfluoroalkyl substances (PFAS) exposureSevere acute respiratory syndrome corona virus 2 (SARS-CoV-2)

Identifiers

PMID42489921
PMCPMC13453976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.