Evidence map›Paper›PMID 42489881›Full record

ReviewHerzschrittmachertherapie & Elektrophysiologie2026

Imaging phenotypes and substrates in ventricular tachycardia.

Pranav Bhagirath, Ivo Roca-Luque

Abstract readReview
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In one paragraph

Review in Herzschrittmachertherapie & Elektrophysiologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pranav BhagirathArrhythmia Section, Institut Clínic Cardiovascular, Hospital Clínic, Universitat de Barcelona, Carrer de Villarroel, 170, L'Eixample, 08036, Barcelona, Spain.
Ivo Roca-LuqueArrhythmia Section, Institut Clínic Cardiovascular, Hospital Clínic, Universitat de Barcelona, Carrer de Villarroel, 170, L'Eixample, 08036, Barcelona, Spain. iroca@clinic.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ventricular tachycardia (VT) remains challenging, as the underlying substrate is heterogeneous and not adequately described by scar burden alone. Imaging is increasingly used to identify structural heart disease, characterize myocardial abnormality, and support VT ablation planning. Distinct imaging findings reflect specific myocardial phenotypes and substrate architectures, such as ischemic scar, nonischemic fibrosis, inflammatory injury, and fibrofatty remodelling. These phenotypes do not represent the same arrhythmic substrate and do not carry the same implications for mechanism, procedural strategy, or follow-up. This review discusses VT in terms of imaging phenotype and substrate rather than scar alone. It also summarizes how imaging can define substrate location, depth, tissue composition, and spatial distribution, and how this may improve understanding of the arrhythmic ventricle. The therapeutic implications of this framework are then discussed, including relevance for treatment planning, interpretation of treatment effect, and assessment of recurrence. Finally, current limitations and future directions of imaging-based substrate assessment in VT are addressed.

Indexed as

Tachycardia, VentricularCatheter AblationEvidence-Based MedicineHumansMagnetic Resonance ImagingPhenotypeArrhythmogenic substrateCardiac imagingCatheter ablationMRIVentricular tachycardia

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.