ArticleThe patient2026
Patient Preferences for Inflammatory Bowel Disease Treatment: Results from a Global Survey Conducted in Partnership with the European Federation of Crohn's & Ulcerative Colitis Associations.
Article in The patient, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
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Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundAs therapeutic options for inflammatory bowel disease (IBD) expand, understanding patient preferences-and how these vary across subgroups-is critical for patient-centered drug development and evaluation. This patient preference study aimed to (1) determine the relative preference weights of IBD treatment- and disease-related attributes (i.e., which features most influence patients' treatment choices) and (2) explain preference heterogeneity.
methodsA survey incorporating a discrete choice experiment (DCE) was disseminated worldwide. Patients repeatedly chose between hypothetical treatment profiles varying across 14 attributes using a partial profile design. The survey design was informed by literature review, qualitative research, and advisory boards. Mixed logit models were applied.
resultsData from 1452 patients (51.0% Crohn's disease [CD]; 49.0% ulcerative colitis/IBD-unclassified [UC/IBD-U]; mean age 42.5 years; 69.0% female) from 40 countries were analyzed. Psychological impact, abdominal pain and cramps, and bowel urgency were the most influential factors in decision-making. Mode of administration, endoscopic remission, and speed of onset were least influential. Patients with UC/IBD-U attached more importance to surgical risk, toilet-related symptoms, psychological impact, physical changes, and infection risk, whereas CD patients placed greater weight on mode of administration. Significant preference heterogeneity was observed and was partly explained by age, time since diagnosis, gender, geographical region, treatment status, treatment classes received, advanced therapy use, and surgery history.
conclusionsIBD patients prioritize psychological well-being and gastrointestinal symptom relief over features distinguishing treatments such as administration method or onset of action. Findings underscore the need to integrate quality-of-life and symptom-based outcomes alongside inflammatory control into trial design, regulatory assessment, and health technology evaluation.
Identifiers
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Registered trials
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