Evidence map›Paper›PMID 42489802›Full record

ArticleJournal of autism and developmental disorders2026

The Empathy Quotient and Systemising Quotient for Toddlers: Development and Validation.

Yumnah T Khan, Alex Tsompanidis, Luning Sun, Carrie Allison, Simon Baron-Cohen

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Article in Journal of autism and developmental disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yumnah T KhanAutism Research Centre, Department of Psychiatry, University of Cambridge, Douglas House, 18B Trumpington Road, Cambridge, Cambridgeshire, CB2 8AH, UK. yk415@cam.ac.uk.ORCID http://orcid.org/0009-0009-2409-8392
Alex TsompanidisAutism Research Centre, Department of Psychiatry, University of Cambridge, Douglas House, 18B Trumpington Road, Cambridge, Cambridgeshire, CB2 8AH, UK.
Luning SunThe Psychometrics Centre, Cambridge Judge Business School, University of Cambridge, Cambridge, UK.
Carrie AllisonAutism Research Centre, Department of Psychiatry, University of Cambridge, Douglas House, 18B Trumpington Road, Cambridge, Cambridgeshire, CB2 8AH, UK.
Simon Baron-CohenAutism Research Centre, Department of Psychiatry, University of Cambridge, Douglas House, 18B Trumpington Road, Cambridge, Cambridgeshire, CB2 8AH, UK.

Funding

Innovative Medicine Joint 2 Undertaking 777394NIHR Cambridge Biomedical Research Centre NIHR203312Wellcome Trust 214322\Z\18\Z
6 · The paper itself

Abstract

purposeEmpathy and systemising are traits that show on-average differences between autistic and non-autistic groups and have informed major theoretical frameworks of autism. While these constructs have been researched extensively in older age groups, no equivalent questionnaire-based measures exist for toddlers.

methodsHere, we developed and validated toddler (T) versions of the Empathy Quotient (EQ-T) and Systemising Quotient (SQ-T) in 1,005 toddlers (572 males, 433 females) aged 1.5 to 4 years (mean = 32.75 months). Parents completed these online along with the Quantitative Checklist for Autism in Toddlers (Q-CHAT), which measures autistic traits.

resultsResults indicated that (a) the EQ-T and SQ-T show good reliability, (b) EQ-T scores negatively predicted and SQ-T scores positively predicted autistic traits, and (c) on average, EQ-T scores were higher in females (d = 0.16), while no significant sex differences were observed in SQ-T scores (d = -0.09).

conclusionThese newly validated measures open various further avenues to better understand the early profiles and developmental pathways associated with autism.

Indexed as

AutismDevelopmentEmpathySystemisingToddlerhood

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.