ArticleFrontiers in veterinary science2026
Cross-protection conferred by intradermal PRRSV-1 modified live vaccine against a highly virulent Vietnamese PRRSV-2 strain in pigs.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Porcine reproductive and respiratory syndrome (PRRS) remain one of the most economically significant diseases affecting the global swine industry. Caused by the PRRS virus (PRRSV), the disease leads to reproductive failure in sows and respiratory disorders in pigs of all ages. In Vietnam, PRRSV was officially reported in 2007, and the emergence of highly pathogenic PRRSV (HP-PRRSV) strains has since intensified outbreaks with high morbidity and mortality. This study evaluated the efficacy of the intradermal PRRSV-1 commercial vaccine (UNISTRAIN® PRRS, HIPRA) in piglets experimentally challenged with a Vietnamese HP-PRRSV-2 strain. Twenty-eight PRRS naïve, 21-day-old piglets were randomly assigned to a VC group, including vaccinated and challenged pigs (
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