Evidence map›Paper›PMID 42488756›Full record

ArticleBrain communications2026

Communication makes intensive language therapy more efficient: a randomized controlled trial in chronic post-stroke aphasia.

Friedemann Pulvermüller, Anna-Thekla Jäger, Milena R Osterloh, Johanna Knechtges, Verena Arndt, Anna Sadlon, Marcelo L Berthier, Bettina Mohr

Abstract read
In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Friedemann PulvermüllerBrain Language Laboratory, Department of Philosophy and Humanities, Freie Universität Berlin, Berlin 14195, Germany.ORCID https://orcid.org/0000-0003-3210-7112
Anna-Thekla JägerBrain Language Laboratory, Department of Philosophy and Humanities, Freie Universität Berlin, Berlin 14195, Germany.
Milena R OsterlohBrain Language Laboratory, Department of Philosophy and Humanities, Freie Universität Berlin, Berlin 14195, Germany.ORCID https://orcid.org/0009-0007-9616-1077
Johanna KnechtgesBrain Language Laboratory, Department of Philosophy and Humanities, Freie Universität Berlin, Berlin 14195, Germany.
Verena ArndtBrain Language Laboratory, Department of Philosophy and Humanities, Freie Universität Berlin, Berlin 14195, Germany.
Anna SadlonBrain Language Laboratory, Department of Philosophy and Humanities, Freie Universität Berlin, Berlin 14195, Germany.
Marcelo L BerthierCognitive Neuroscience and Aphasia Unit, Faculty of Psychology and Speech Therapy, University of Malaga, 29071 Malaga, Spain.ORCID https://orcid.org/0000-0002-6393-3487
Bettina MohrBrain Language Laboratory, Department of Philosophy and Humanities, Freie Universität Berlin, Berlin 14195, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Speech-language therapy is effective in chronic post-stroke aphasia if it is delivered in an intensive fashion. The study investigated whether intensive communicative therapy by practicing everyday language use (e.g. requesting objects and proposing actions) leads to better outcomes than equally intensive conventional treatment (e.g. picture naming). A randomized controlled trial compared intensive conventional speech-language therapy to a social-communicative treatment, called Intensive Language Action Therapy, a further development of Constraint-Induced Aphasia Therapy. Forty-four chronic post-stroke aphasia patients randomized to one of these treatments received 2 weeks, 5 days/week, for 2.5 h/day of therapy. Primary outcome measure was an established clinical language battery. To address any changes in mood, patients' depressive symptoms were assessed using Beck's Depression Inventory. A significant interaction [

Indexed as

communicationdepressionintensive speech-language therapyneurorehabilitationpost-stroke aphasia

Identifiers

PMID42488756
PMCPMC13390638

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.