ReviewOncology letters2026
Gastrointestinal conventional carcinoma with neuroendocrine differentiation: From pathological phenomenon to clinical importance (Review).
Review in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
8 authors.
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Abstract
Conventional carcinomas that lack neuroendocrine morphological features but display detectable expression of neuroendocrine markers through immunohistochemistry are termed conventional carcinomas with neuroendocrine differentiation (NED). Distinguishing these from mixed neuroendocrine non-neuroendocrine neoplasms and amphicrine-like carcinomas is important in accurate diagnosis and clinical management. The present review systematically outlines the advancements in research on gastrointestinal conventional carcinomas with NED, focusing on their characteristics, diagnostic criteria and clinical features. The present review further summarizes the epidemiological and clinical aspects across numerous organs such as the stomach and colorectum, emphasizing common mechanisms and prognostic variability. The future prospects of gastrointestinal conventional carcinomas with NED are also discussed, concentrating on key mechanisms, molecular subtypes and ongoing clinical trials to influence future research and clinical practices.
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