Evidence map›Paper›PMID 42488540›Full record

ReviewFrontiers in cardiovascular medicine2026

Contemporary extracorporeal cardiopulmonary resuscitation programs for cardiac arrest.

Samuele Bugo, Alice Bottussi, Jacopo D'Andria Ursoleo, Marta Velia Antonini, Erika Cordella, Myriam Aprile, Samuel I Garcia, Omar Elmadhoun, Erin D Wieruszewski, Justyna Swol and 2 more

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Samuele Bugo *Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Alice Bottussi *Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Jacopo D'Andria Ursoleo *Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Marta Velia AntoniniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Erika CordellaCoordination for Transplants' Center (CRT-ER), IRCCS Azienda Ospedaliero-Università di Bologna, Bologna, Italy.
Myriam AprileDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Samuel I GarciaDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, United States.
Omar ElmadhounDepartment of Anesthesiology, Mayo Clinic, Rochester, MN, United States.
Erin D WieruszewskiDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN, United States.
Justyna SwolDepartment of Respiratory Medicine, Paracelsus Medical University, Nuremberg, Germany.
Patrick M WieruszewskiDepartment of Anesthesiology, Mayo Clinic, Rochester, MN, United States.
Fabrizio MonacoDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac arrest is a leading cause of global mortality, with low survival rates despite advances in resuscitation science. Reported survival ranges from 8% to 34% for out-of-hospital and in-hospital cardiac arrest. Extracorporeal cardiopulmonary resuscitation (ECPR) has emerged as a rescue therapy for patients unresponsive to conventional CPR, leveraging veno-arterial extracorporeal membrane oxygenation (ECMO) to provide artificial circulation, gas exchange, and maintenance of organ perfusion in the absence of spontaneous native circulation. Successful ECPR depends on minimizing time to ECMO initiation and selecting appropriate patients. While several aspects are consistent across countries, ECPR protocols vary in logistics, team composition, cannulation methods, and monitoring, which may influence patient-important outcomes such as survival and neurological recovery. This narrative review explores current global practices in ECPR, and identifies opportunities for standardization while recognizing elements that should remain context specific.

Indexed as

cardiac arrestcritical careECPR programsemergency servicesextracorporeal cardiopulmonary resuscitationout-of-hospital cardiac arrest

Identifiers

PMID42488540
PMCPMC13388891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.