Evidence map›Paper›PMID 42488509›Full record

ReviewInternational journal of burns and trauma2026

Evaluating the electrocardiographic abnormalities in traumatic brain injury: prevalence, severity correlation, and outcome prediction.

Azad Mojahedi, Moshe Gunsburg, Adam Friedman, Mustafa Abomohsen, Meena Farid, Iyad Idries, Hal Chadow

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of burns and trauma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Azad MojahediCardiology Department, Brookdale University Hospital and Medical Center Brooklyn, New York, USA.
Moshe GunsburgCardiology Department, Brookdale University Hospital and Medical Center Brooklyn, New York, USA.
Adam FriedmanCardiology Department, Brookdale University Hospital and Medical Center Brooklyn, New York, USA.
Mustafa AbomohsenCardiology Department, Brookdale University Hospital and Medical Center Brooklyn, New York, USA.
Meena FaridCardiology Department, Brookdale University Hospital and Medical Center Brooklyn, New York, USA.
Iyad IdriesCardiology Department, Brookdale University Hospital and Medical Center Brooklyn, New York, USA.
Hal ChadowCardiology Department, Brookdale University Hospital and Medical Center Brooklyn, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraumatic brain injury (TBI) induces systemic responses, including neurogenic cardiac injury via the brain-heart axis, manifesting as electrocardiographic (ECG) abnormalities that may predict outcomes.

objectiveThis systematic review aimed to evaluate the diagnostic and prognostic utility of ECG monitoring in patients with TBI, identify knowledge gaps, and guide future research.

methodsFollowing PRISMA guidelines, we searched PubMed and Google Scholar (January 2020 - March 2025) for studies on adult patients with TBI (≥ 16 years) who underwent acute ECG assessment (≤ 72 hours post-injury). The inclusion criteria focused on observational/cohort studies that reported ECG changes, severity correlations, and outcomes. The exclusion criteria were pediatric cases, pre-existing cardiac conditions, and non-English articles. Data were extracted from the eligible studies.

resultsSix studies (1,642 patients) revealed ECG abnormalities in 10-88% of cases, increasing with TBI severity (e.g., prolonged QTc in 3% of mild cases vs. 15% of severe cases). Common changes included repolarization issues (QTc prolongation and ST-segment/T-wave alterations), arrhythmias, and conduction disturbances. Abnormalities often resolved within days, improved post-neurosurgery (e.g., reduced QTc), and predicted mortality (e.g., QTc prolongation/ST depression as independent factors) and cardiac dysfunction.

conclusionECG changes are prevalent in TBI, correlate with severity, and have prognostic value for risk stratification. Routine monitoring is recommended, and larger, standardized studies are needed to optimize management.

Indexed as

cardiac dysfunctioncardiac functionelectrocardiogramTraumatic brain injury

Identifiers

PMID42488509
PMCPMC13389655

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.