Evidence map›Paper›PMID 42488473›Full record

ArticleJournal of biomedical optics2026

Autonomous robotic alignment and dynamic illumination control of an ophthalmic slit lamp for

Morgan McCloud, Nipun Hewage, Joseph A Izatt, Mark Draelos, Anthony N Kuo, Ryan P McNabb

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Morgan McCloudDuke University, Department of Biomedical Engineering, Durham, North Carolina, United States.ORCID https://orcid.org/0000-0001-7406-2261
Nipun HewageDuke University Medical Center, Department of Ophthalmology, Durham, North Carolina, United States.
Joseph A IzattDuke University, Department of Biomedical Engineering, Durham, North Carolina, United States.
Mark DraelosUniversity of Michigan, Department of Robotics, Ann Arbor, Michigan, United States.ORCID https://orcid.org/0000-0002-5051-0880
Anthony N KuoDuke University, Department of Biomedical Engineering, Durham, North Carolina, United States.
Ryan P McNabbDuke University Medical Center, Department of Ophthalmology, Durham, North Carolina, United States.ORCID https://orcid.org/0000-0002-1686-4191

Funding

Self-aligning, motion-stabilized ocular imaging for eye care in urgent and emergent care settingsR01EY035534 · NEI · DUKE UNIVERSITY · PI Anthony Nanlin Kuo · 2023 to 2026
$1.5M
NRI: Toward Safe and Reliable Robotic Eye ExaminationsR01EY035106 · NEI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HAUSER, KRIS, KUO, ANTHONY NANLIN · 2023 to 2025
$1.2M
Robotic Point-of-Care OCTR00EY034200 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DRAELOS, MARK · 2023 to 2025
$747k
NEI NIH HHS R00 EY034200NEI NIH HHS R01 EY035106NEI NIH HHS R01 EY035534
6 · The paper itself

Abstract

Significance: The slit lamp is the gold standard ophthalmic instrument for examining the anterior segment of the eye. Slit lamps require the mechanical stabilization of patients to facilitate alignment and a specialized technician to operate. The growing demand for ophthalmic care and shortages of specialists highlight the need for alternative diagnostic technologies. Aim: We demonstrate an autonomously aligning, contactless slit lamp enabled by a vision-guided robot to acquire anterior segment images without mechanical patient stabilization. Approach: We integrate three subsystems mounted to a collaborative robot arm: a custom optical system for dynamic slit illumination, vision-based sensors, and color cameras. A hierarchical control strategy is employed to maintain alignment. Programmable illumination patterns are projected onto the cornea to replicate slit-lamp examination maneuvers. Results: The device autonomously aligned to the eyes of Conclusions: These results demonstrate the feasibility of autonomous, contactless slit-lamp imaging through the use of robotic alignment and dynamic illumination. Such advancements could expand access to anterior segment diagnostic imaging.

Indexed as

Anterior Eye SegmentImage Processing, Computer-AssistedRoboticsSlit LampSlit Lamp MicroscopyAutonomous RobotsEquipment DesignHumansautomatic alignmentillumination engineeringmedical robotsophthalmic imagingslit lamp

Identifiers

PMID42488473
PMCPMC13391205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.