Evidence map›Paper›PMID 42488425›Full record

ArticleFrontiers in cellular and infection microbiology2026

Combined NGS and proteomics improves viral diagnostics in wildlife: coronaviruses confirmed in hedgehogs.

Ivan Chudinov, Elena Korneenko, Irina Rog, Alexandra Lukina-Gronskaya, Alexey Kovalenko, Veronika Gremyacheva, Ivan Butenko, Elena Vasileva, Daria Matyushkina, Elena Litvinova and 2 more

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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ivan ChudinovLaboratory of Multiomics Research, Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Elena KorneenkoLaboratory of Multiomics Research, Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Irina RogLaboratory of Multiomics Research, Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Alexandra Lukina-GronskayaLaboratory of Multiomics Research, Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Alexey KovalenkoLaboratory of Multiomics Research, Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Veronika GremyachevaLaboratory of Multiomics Research, Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Ivan ButenkoLaboratory of Multiomics Research, Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Elena VasilevaLaboratory of Simple Systems, Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Daria MatyushkinaLaboratory of Simple Systems, Scientific Research Institute for Systems Biology and Medicine, Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia.
Elena LitvinovaBiological Department, Lomonosov Moscow State University, Moscow, Russia.
Natalia FeoktistovaA.N. Severtsov Institute of Ecology and Evolution of the Russian Academy of Science, Moscow, Russia.
Anna SperanskayaLaboratory of DNA Methylome and Transcriptome Editing, Vavilov Institute of General Genetics Russian Academy of Science, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Metaviromic sequencing is prone to artifacts, necessitating orthogonal validation. This study evaluates a targeted proteogenomic approach for verifying viral presence initially detected by NGS. Methods: We analyzed oropharyngeal/anal swabs and feces from hedgehogs, where NGS indicated viruses from the Results: Proteomic analysis confirmed Discussion: Phylogenetic analysis of two complete

Indexed as

Animals, WildCoronavirusHedgehogsHigh-Throughput Nucleotide SequencingProteomicsAnimalsFecesGenome, ViralPhylogenybetacoronavirusesCoronaviridaehedgehogshigh-throughput sequencingPicornaviridaeproteogenomicsproteomics

Identifiers

PMID42488425
PMCPMC13388059

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.